Chiral HPLC Columns

Daicel's chiral HPLC columns are the most widely used chiral chromatography products in the world. Because of their exceptionally high durability, high power capacity, versatility and excellent separation performance, they are used primarily in HPLC as well as supercritical fluid chromatography (SFC). In addition, chiral stationary phases (CSPs) have become the first choice for enatiomer analysis and separation of chiral substances. The columns are available in a wide variety of configurations. To find the column you need more quickly and easily, use the filter options on the left or our HPLC column configurator.

Learn more about Daicel's column families.

Items 1-50 of 915

Product Image of HPLC column CHIRALPAK AGP, 100 x 3 mm, 5 µm
HPLC column CHIRALPAK AGP, 100 x 3 mm, 5 µm
Item number: DAIC30783
Brand: Chiral

In stock

€1,235.00 €1,300.00
Product Image of HPLC column CHIRALPAK AGP, 50 x 3 mm, 5 µm
HPLC column CHIRALPAK AGP, 50 x 3 mm, 5 µm
Item number: DAIC30782
Brand: Chiral

In stock

€973.75 €1,025.00
Product Image of HPLC Guard CHIRALPAK AGP, 10 x 3 mm, 5 µm, 2 pc/pak
HPLC Guard CHIRALPAK AGP, 10 x 3 mm, 5 µm, 2 pc/pak
Item number: DAIC30781
Brand: Chiral

In stock

€223.25 €235.00
Product Image of HPLC column CHIRALPAK AGP, 150 x 4 mm, 5 µm
HPLC column CHIRALPAK AGP, 150 x 4 mm, 5 µm
Item number: DAIC30714
Brand: Chiral

In stock

€1,619.75 €1,705.00
Product Image of HPLC Column CHIRALPAK AGP, 100 x 4 mm, 5 µm
HPLC Column CHIRALPAK AGP, 100 x 4 mm, 5 µm
Item number: DAIC30713
Brand: Chiral

In stock

€1,235.00 €1,300.00
Product Image of HPLC column CHIRALPAK AGP, 50 x 4 mm, 5 µm
HPLC column CHIRALPAK AGP, 50 x 4 mm, 5 µm
Item number: DAIC30712
Brand: Chiral

In stock

€973.75 €1,025.00
Product Image of HPLC Guard CHIRALPAK AGP, 10 x 4 mm, 5 µm, 2 pc/pak
HPLC Guard CHIRALPAK AGP, 10 x 4 mm, 5 µm, 2 pc/pak
Item number: DAIC30711
Brand: Chiral

In stock

€256.50 €270.00
Product Image of HPLC Column CHIRALPAK® AD-3, 250 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® AD-3, 250 x 4,6 mm, 3 µm
Item number: DAIC19525
Brand: Chiral

In stock

€1,738.50 €1,830.00
Product Image of HPLC Column CHIRALPAK® AD-3, 150 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® AD-3, 150 x 4,6 mm, 3 µm
Item number: DAIC19524
Brand: Chiral

In stock

€1,738.50 €1,830.00
Product Image of HPLC Column CHIRALPAK® AD-3, 100 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® AD-3, 100 x 4,6 mm, 3 µm
Item number: DAIC19523
Brand: Chiral

In stock

€1,372.75 €1,445.00
Product Image of HPLC Column CHIRALPAK® AD-3, 50 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® AD-3, 50 x 4,6 mm, 3 µm
Item number: DAIC19522
Brand: Chiral

In stock

€1,007.00 €1,060.00
Product Image of HPLC Guard Cartridge CHIRALPAK® AD-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® AD-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC19511
Brand: Chiral

In stock

€361.00 €380.00
Product Image of HPLC Column CHIRALPAK® AD-H, 250 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® AD-H, 250 x 4,6 mm, 5 µm
Item number: DAIC19325
Brand: Chiral

In stock

€1,738.50 €1,830.00
Product Image of HPLC Column CHIRALPAK® AD-H, 150 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® AD-H, 150 x 4,6 mm, 5 µm
Item number: DAIC19324
Brand: Chiral

In stock

€1,738.50 €1,830.00
Product Image of HPLC Guard Cartridge CHIRALPAK® AD-H, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® AD-H, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC19311
Brand: Chiral

In stock

€361.00 €380.00
Product Image of HPLC Column CHIRALPAK AD, 250 x 4.6 mm, 10 µm
HPLC Column CHIRALPAK AD, 250 x 4.6 mm, 10 µm
Item number: DAIC19025
Brand: Chiral

In stock

€1,738.50 €1,830.00
Product Image of HPLC Column CHIRALCEL® OD-3, 150 x 4,6 mm, 3 µm
HPLC Column CHIRALCEL® OD-3, 150 x 4,6 mm, 3 µm
Item number: DAIC14524
Brand: Chiral

In stock

€1,738.50 €1,830.00
Product Image of HPLC Column CHIRALCEL® OD-3, 100 x 4,6 mm, 3 µm
HPLC Column CHIRALCEL® OD-3, 100 x 4,6 mm, 3 µm
Item number: DAIC14523
Brand: Chiral

In stock

€1,372.75 €1,445.00
Product Image of HPLC Column CHIRALCEL® OD-3, 50 x 4,6 mm, 3 µm
HPLC Column CHIRALCEL® OD-3, 50 x 4,6 mm, 3 µm
Item number: DAIC14522
Brand: Chiral

In stock

€1,007.00 €1,060.00
Product Image of HPLC  Guard Cartridge CHIRALCEL® OD-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALCEL® OD-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC14511
Brand: Chiral

In stock

€361.00 €380.00
Product Image of HPLC Column CHIRALCEL® OD-H, 250 x 4,6 mm, 5 µm
HPLC Column CHIRALCEL® OD-H, 250 x 4,6 mm, 5 µm
Item number: DAIC14325
Brand: Chiral

In stock

€1,738.50 €1,830.00
Product Image of HPLC Column CHIRALCEL® OD-H, 150 x 4,6 mm, 5 µm
HPLC Column CHIRALCEL® OD-H, 150 x 4,6 mm, 5 µm
Item number: DAIC14324
Brand: Chiral

In stock

€1,738.50 €1,830.00
Product Image of HPLC  Guard Cartridge CHIRALCEL® OD-H, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALCEL® OD-H, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC14311
Brand: Chiral

In stock

€361.00 €380.00
Product Image of HPLC Column CHIRALCEL® OD, 250 x 4,6 mm, 10 µm
HPLC Column CHIRALCEL® OD, 250 x 4,6 mm, 10 µm
Item number: DAIC14025
Brand: Chiral

In stock

€1,738.50 €1,830.00
Product Image of HPLC Column CHIRALPAK IG-3, 150 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IG-3, 150 x 3 mm, 3 µm, SFC
Item number: DAIC87S84
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK IG-3, 100 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IG-3, 100 x 3 mm, 3 µm, SFC
Item number: DAIC87S83
Brand: Chiral

In stock

€1,490.00
Product Image of HPLC Column CHIRALPAK IG-3, 50 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IG-3, 50 x 3 mm, 3 µm, SFC
Item number: DAIC87S82
Brand: Chiral

In stock

€1,090.00
Product Image of HPLC Column CHIRALPAK® IG-3, 250 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IG-3, 250 x 4,6 mm, 3 µm
Item number: DAIC87525
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IG-3, 150 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IG-3, 150 x 4,6 mm, 3 µm
Item number: DAIC87524
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IG-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IG-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC87511
Brand: Chiral

In stock

€390.00
Product Image of HPLC Column CHIRALPAK® IG, 250 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® IG, 250 x 4,6 mm, 5 µm
Item number: DAIC87325
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IG, 150 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® IG, 150 x 4,6 mm, 5 µm
Item number: DAIC87324
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IG, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IG, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC87311
Brand: Chiral

In stock

€390.00
Product Image of HPLC Column CHIRALPAK IF-3, 150 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IF-3, 150 x 3 mm, 3 µm, SFC
Item number: DAIC86S84
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK IF-3, 100 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IF-3, 100 x 3 mm, 3 µm, SFC
Item number: DAIC86S83
Brand: Chiral

In stock

€1,490.00
Product Image of HPLC Column CHIRALPAK IF-3, 50 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IF-3, 50 x 3 mm, 3 µm, SFC
Item number: DAIC86S82
Brand: Chiral

In stock

€1,090.00
Product Image of HPLC Column CHIRALPAK® IF-3, 250 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IF-3, 250 x 4,6 mm, 3 µm
Item number: DAIC86525
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IF-3, 150 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IF-3, 150 x 4,6 mm, 3 µm
Item number: DAIC86524
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IF-3, 100 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IF-3, 100 x 4,6 mm, 3 µm
Item number: DAIC86523
Brand: Chiral

In stock

€1,490.00
Product Image of HPLC Column CHIRALPAK® IF-3, 50 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IF-3, 50 x 4,6 mm, 3 µm
Item number: DAIC86522
Brand: Chiral

In stock

€1,090.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IF-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IF-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC86511
Brand: Chiral

In stock

€390.00
Product Image of HPLC Column CHIRALPAK® IF, 250 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® IF, 250 x 4,6 mm, 5 µm
Item number: DAIC86325
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IF, 150 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® IF, 150 x 4,6 mm, 5 µm
Item number: DAIC86324
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Guard Cartridge CHIRALPAK IF, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK IF, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC86311
Brand: Chiral

In stock

€390.00
Product Image of HPLC Column CHIRALPAK IE-3, 150 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IE-3, 150 x 3 mm, 3 µm, SFC
Item number: DAIC85S84
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK IE-3, 100 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IE-3, 100 x 3 mm, 3 µm, SFC
Item number: DAIC85S83
Brand: Chiral

In stock

€1,490.00
Product Image of HPLC Column CHIRALPAK IE-3, 50 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IE-3, 50 x 3 mm, 3 µm, SFC
Item number: DAIC85S82
Brand: Chiral

In stock

€1,090.00
Product Image of HPLC Column CHIRALPAK® IE-3, 250 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IE-3, 250 x 4,6 mm, 3 µm
Item number: DAIC85525
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IE-3, 150 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IE-3, 150 x 4,6 mm, 3 µm
Item number: DAIC85524
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IE-3, 100 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IE-3, 100 x 4,6 mm, 3 µm
Item number: DAIC85523
Brand: Chiral

In stock

€1,490.00

Immobilised Chiralpak

Immobilised Chiralpak HPLC and SFC columns are packed with new Chiral Stationary Phases - consisting of a silica support onto which the polymeric chiral selector (polysaccharide derivatives) has been immobilised. Immobilisation of the polysaccharide derivatives on a matrix is an excellent approach to provide universal solvent compatibility on these highly selective Chiral Stationary Phases. This broadens the range of solvents to be used as mobile phases, thereby introducing new selectivity profiles, improved productivity and robustness in use.

Phase Particle Size in µm Phase Particle Size in µm
Chiralpak IA 3 | 5 Chiralpak IB SFC 3.5
Chiralpak IA SFC 3.5 Chiralpak IC 3 | 5
Chiralpak IB 3 | 5 Chiralpak IC SFC 3.5

Coated Chiralpak

The predecessors to the new generation of immobilised columns, traditional CHIRALPAK and CHIRALCEL coated polysaccharide Chiral Stationary Phases are made with a spherical high quality silica support onto which the polymeric chiral selector (amylose or cellulose derivatives) is physically coated. Due to the coated nature of these chiral supports, solvents should be carefully selected.

Phase Particle Size in µm Phase Particle Size in µm
Chiralpak AD 3 | 10 Chiralpak AS 3 | 10
Chiralpak AD-H 5 Chiralpak AS-H 5
Chiralpak AZ 3 Chiralpak AY 3
Chiralpak AZ-H 5 Chiralpak AY-H 5

Coated Chiralcel

The predecessors to the new generation of immobilised columns, traditional CHIRALPAK and CHIRALCEL coated polysaccharide Chiral Stationary Phases are made with a spherical high quality silica support onto which the polymeric chiral selector (amylose or cellulose derivatives) is physically coated. Due to the coated nature of these chiral supports, solvents should be carefully selected.

Phase Particle Size in µm Phase Particle Size in µm
Chiralcel OA 10 Chiralcel OF 10
Chiralcel OB 10 Chiralcel OG 10
Chiralcel OB-H 5 Chiralcel OJ 3 | 10
Chiralcel OC 10 Chiralcel OJ-H 5
Chiralcel OC-H 5 Chiralcel OK 10
Chiralcel OD 3 | 10 Chiralcel OZ 3
Chiralcel OD-H 5 Chiralcel OZ-H 5

Reverse Phase Chiralpak

CHIRALPAK® -3R & [-RH] & CHIRALCEL® -R & [-RH] have been developed by DAICEL as the reverse phase versions of CHIRALPAK® AD-H, AS-H, AY-H, AZ-H & CHIRALCEL® OD-H, OJ-H, OZ-H (Columns which have the widest applicability in normal phase mode). They have the same coated chiral selector as found in the normal phase stationary phases, but are coated to a hydrophobic high quality silica support.

Phase Particle Size in µm Phase Particle Size in µm
Chiralpak AD-3R 3 Chiralpak AS-RH 5
Chiralpak AD-RH 5 Chiralpak AY-3R 3
Chiralpak AS-3R 3 Chiralpak AZ-3R 2

Reverse Phase Chiralcel

CHIRALPAK® -3R & [-RH] & CHIRALCEL® -R & [-RH] have been developed by DAICEL as the reverse phase versions of CHIRALPAK® AD-H, AS-H, AY-H, AZ-H & CHIRALCEL® OD-H, OJ-H, OZ-H (Columns which have the widest applicability in normal phase mode). They have the same coated chiral selector as found in the normal phase stationary phases, but are coated to a hydrophobic high quality silica support.

Phase Particle Size in µm Phase Particle Size in µm
Chiralcel OD-3R 3 Chiralcel OJ-3R 3
Chiralcel OD-RH 5 Chiralcel OJ-RH 5
Chiralcel OD-R 10 Chiralcel OZ-3R 3

Chiralpak

These two phases, QD-AX and QN-AX, are based on two complementary stereoisomeric quinine (qN) and quinidine (qD) derivatives. Due to their pseudo enantiomeric character they usually reveal reversed elution order for opposite enantiomers.
The Chiral Stationary Phases, WH and MA(+), in these columns are made of amino acids and its derivatives coated bonded to silica supports (with a particle size of 10 μm for WH and 3 μm for MA(+)). Since these columns are ligand-exchange type columns, the standard mobile phase to use is an aqueous solution of CuSO4 (0.1 to 2mM). These columns can tolerate organic modifiers such as Methanol and Acetonitrile according specifications in the instruction manual. 

Phase Particle Size in µm Phase Particle Size in µm
Chiralpak QD-AX 5 Chiralpak WH 10
Chiralpak QN-AX 5 Chiralpak MA(+) 3

Crownpak

These columns contain a chiral crown ether as a chiral selector, which is coated onto a 5 μm support. Acidic mobile phases such as Perchloric acid pH 1 to 2, are used to operate these columns under standard conditions. Note that to shorten the retention time of hydrophobic samples, the addition of Methanol (15% maximum v/v) has been shown to be effective. These columns are the reference columns for achieving amino acid separations, with the advantage the elution order of the enantiomers can be reversed when necessary (CR(-) column gives the reversed elution order compared to CR(+) column).

Phase Particle Size in µm Phase Particle Size in µm
Crownpak CR(+) 5 Crownpak CR(-) 5

Chromtech Chiral

These protein-based columns are suitable for several types of compounds; basic compounds can be separated on both CHIRAL-AGP and CHIRAL-CBH, acidic and neutral compounds can be separated on both CHIRAL-AGP and CHIRAL-HSA. However, as CHIRAL-AGP is a column with an extremely broad applicability, this column should be chosen first, if the analyte has not been separated on any of the columns.

Phase Particle Size in µm Phase Particle Size in µm
Chromtech AGP 5 Chromtech HSA 5
Chromtech CBH 5