HPLC Mini Column Kit IAM Fast-Screen, 10 µm, 3 x 10 mm

Contains 2 columns and 1 holder.

IAM Drug Discovery HPLC Column is an ideal tool for high throughput prediction of drug membrane permeability. The results from this column correlate well to traditional in-vitro methods such as intestinal tissue and Caco-2 Cells, yet are faster and cheaper to achieve.

Phosphatidylcholine (PC) is the major phospholipid found in cell membranes. lAM chromatography phases prepared from PC analogs closely mimic the surface of a biological cell membrane. Consequently, IAM phases display a high affinity for membrane proteins and are useful in membrane protein purification and in the study of drug-membrane interactions.