BSTFA GC Silylation Reagent, 1 ml ampule, 10 pc/pak

Improve your GC analysis with Thermo Scientific™ BSTFA silylation reagent. The highly volatile byproducts bis(trimethylsilyl)trifluoroacetamide (BSTFA) and trifluoroacetamide elute with the solvent front, providing excellent chromatographic separations. This silylation reagent reacts with a wide range of polar compounds and is particularly well suited for the GC analysis of certain low boiling point TMS amino acids and TMS citrate cyclic acids.

BSTFA is a powerful trimethylsilyl donor with donor strength comparable to its non-fluorinated analogue, BSA [N,O-bis(trimethylsilyl)acetamide]. BSTFA replaces labile hydrogens in a wide range of polar compounds with a -Si(CH3)3 group during the reaction. This physical property is particularly useful in the gas chromatography of some low boiling point TMS amino acids and TMS citrate cyclic acids.

Increased volatility of the reaction byproducts mono(trimethylsilyl)trifluoroacetamide and trifluoroacetamide over corresponding non-fluorinated BSA compounds
Increased volatility allows the derivatization of small molecules with which the TMS derivatives co-elute with the byproducts of BSA.