Key feature of UP-SW3000-LS UHPLC columns is a highly reduced noise level in advanced detectors saving time for equilibration and improving data quality. For multi-angle light scattering (MALS) applications, a low noise level is achieved in minutes, leading to high signal-to-noise ratios and thus high sensitivity. For mass spectrometry applications, ionization efficiency by electrospray ionization is improved and increases overall MS performance and instrument uptime. This makes the UP-SW3000-LS column particularly suited for in-depth analyses of aggregates and fragments of mAbs, bi- and multispecifics. In addition, the UP-SW3000-LS columns offer reproducible and reliable size exclusion protein separations. This is explained by robust separations over multiple injections as well as a high column lifetime which reduces the need for frequent column replacements. However, low variations between column production lots facilitate column exchange.
More Information
Additional
Brand
Tosoh Bioscience
Column description
TSKgel
Package specification
(OH) Diol
Inner diameter
4.6 mm
mode
Normal Phase (NP)
Particle Size
2,0 µm
pH Range
2,5 - 7,5
Pore size
250 Å
USP number
L20
Length
150 mm
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