LP is abbreviation for Low pH. LP phases are designed for use at low pH conditions. LP phase consists of two very bulky hydrophobic protective groups to prevent siloxane bond from hydrolysis at low pH condition. So Ultisil LP column is extremely stable in very low pH mobile phase and at high temperature, even at the lowest pH of 1.0, making it the most stable phase for low pH application in the market. Because it is not endcapped and has more surface silanols, LP phase has more retention for some early eluted polar compounds, and provides different selectivities . Ultisil LP-C18 is the most polar C18 among all the C18 products of Welch.