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Nacalai HPLC Columns

The Japanese manufacturer Nacalai Tesque is known for its Cosmosil HPLC columns. At Analytics-Shop you will find a wide range of HPLC columns from Nacalai Tesque in various specifications. Please use our HPLC column configurator to find the right column for you.

Items 1-50 of 419

Product Image of HPLC Guard Column COSMOSIL RNA-SEC-2000, packed, 7.5 x 50 mm
HPLC Guard Column COSMOSIL RNA-SEC-2000, packed, 7.5 x 50 mm
Item number: CO-21096-91
Brand: Nacalai Tesque
$1,014.00
Product Image of HPLC Column COSMOSIL RNA-SEC-2000, packed, 7.5 x 300 mm
HPLC Column COSMOSIL RNA-SEC-2000, packed, 7.5 x 300 mm
Item number: CO-19381-11
Brand: Nacalai Tesque
$3,163.20
Product Image of HPLC Column COSMOSIL RNA-SEC-2000, packed, 4.6 x 250 mm
HPLC Column COSMOSIL RNA-SEC-2000, packed, 4.6 x 250 mm
Item number: CO-21095-01
Brand: Nacalai Tesque
$2,277.60
Product Image of HPLC Guard Column COSMOSIL RNA-SEC-1000, packed, 7.5 x 50 mm
HPLC Guard Column COSMOSIL RNA-SEC-1000, packed, 7.5 x 50 mm
Item number: CO-20785-91
Brand: Nacalai Tesque
$1,014.00
Product Image of HPLC Column COSMOSIL RNA-SEC-1000, packed, 7.5 x 300 mm
HPLC Column COSMOSIL RNA-SEC-1000, packed, 7.5 x 300 mm
Item number: CO-19380-21
Brand: Nacalai Tesque
$3,163.20
Product Image of HPLC Column COSMOSIL RNA-SEC-1000, packed, 4.6 x 250 mm
HPLC Column COSMOSIL RNA-SEC-1000, packed, 4.6 x 250 mm
Item number: CO-21088-01
Brand: Nacalai Tesque
$2,277.60
Product Image of HPLC Column COSMOSIL RNA-RP1, packed, 4.6 x 100 mm
HPLC Column COSMOSIL RNA-RP1, packed, 4.6 x 100 mm
Item number: CO-21079-21
Brand: Nacalai Tesque
$2,025.60
Product Image of HPLC Column COSMOSIL RNA-RP1, packed, 2 x 100 mm
HPLC Column COSMOSIL RNA-RP1, packed, 2 x 100 mm
Item number: CO-21078-31
Brand: Nacalai Tesque
$2,025.60
Product Image of HPLC Column COSMOSIL RNA-RP1, packed, 10 x 100 mm
HPLC Column COSMOSIL RNA-RP1, packed, 10 x 100 mm
Item number: CO-21080-81
Brand: Nacalai Tesque
$3,795.60
Product Image of HPLC Column COSMOSIL 5Diol-2000-II, packed, 2000Å, 5 µm, 7.5 x 300 mm
HPLC Column COSMOSIL 5Diol-2000-II, packed, 2000Å, 5 µm, 7.5 x 300 mm
Item number: CO-19976-31
Brand: Nacalai Tesque
$3,739.20
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 4.6 x 75 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 4.6 x 75 mm
Item number: CO-21523-81
Brand: Nacalai Tesque
$817.20
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 4.6 x 50 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 4.6 x 50 mm
Item number: CO-21522-91
Brand: Nacalai Tesque
$817.20
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 4.6 x 250 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 4.6 x 250 mm
Item number: CO-21526-51
Brand: Nacalai Tesque
$1,028.40
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 4.6 x 150 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 4.6 x 150 mm
Item number: CO-21525-61
Brand: Nacalai Tesque
$817.20
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 4.6 x 100 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 4.6 x 100 mm
Item number: CO-21524-71
Brand: Nacalai Tesque
$817.20
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 3 x 75 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 3 x 75 mm
Item number: CO-21513-11
Brand: Nacalai Tesque
$817.20
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 3 x 50 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 3 x 50 mm
Item number: CO-21509-81
Brand: Nacalai Tesque
$817.20
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 3 x 250 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 3 x 250 mm
Item number: CO-21521-01
Brand: Nacalai Tesque
$1,028.40
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 3 x 150 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 3 x 150 mm
Item number: CO-21520-11
Brand: Nacalai Tesque
$646.80
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 3 x 100 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 3 x 100 mm
Item number: CO-21514-01
Brand: Nacalai Tesque
$817.20
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 2 x 75 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 2 x 75 mm
Item number: CO-21496-51
Brand: Nacalai Tesque
$817.20
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 2 x 50 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 2 x 50 mm
Item number: CO-21495-61
Brand: Nacalai Tesque
$817.20
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 2 x 250 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 2 x 250 mm
Item number: CO-21500-71
Brand: Nacalai Tesque
$1,028.40
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 2 x 150 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 2 x 150 mm
Item number: CO-21499-21
Brand: Nacalai Tesque
$817.20
Product Image of HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 2 x 100 mm
HPLC Column COSMOSIL 3πNAP, packed, 120Å, 3 µm, 2 x 100 mm
Item number: CO-21497-41
Brand: Nacalai Tesque
$817.20
Product Image of HPLC Column COSMOSIL 3SL-II, 120 Å, 3 µm, 2 x 250 mm
HPLC Column COSMOSIL 3SL-II, 120 Å, 3 µm, 2 x 250 mm
Item number: CO-19400-51
Brand: Nacalai Tesque
$775.20
Product Image of HPLC Column COSMOSIL 3PBr, 120 Å, 3 µm, 3 x 75 mm
HPLC Column COSMOSIL 3PBr, 120 Å, 3 µm, 3 x 75 mm
Item number: CO-19350-11
Brand: Nacalai Tesque
$798.00
Product Image of HPLC Column COSMOSIL 3PBr, 120 Å, 3 µm, 3 x 50 mm
HPLC Column COSMOSIL 3PBr, 120 Å, 3 µm, 3 x 50 mm
Item number: CO-19349-51
Brand: Nacalai Tesque
$794.40
Product Image of HPLC Column COSMOSIL 3PBr, 120 Å, 3 µm, 3 x 100 mm
HPLC Column COSMOSIL 3PBr, 120 Å, 3 µm, 3 x 100 mm
Item number: CO-19351-01
Brand: Nacalai Tesque
$829.20
Product Image of HPLC Column COSMOSIL 3PBr, 120 Å, 3 µm, 2 x 75 mm
HPLC Column COSMOSIL 3PBr, 120 Å, 3 µm, 2 x 75 mm
Item number: CO-19346-81
Brand: Nacalai Tesque
$799.20
Product Image of HPLC Column COSMOSIL 3PBr, 120 Å, 3 µm, 2 x 100 mm
HPLC Column COSMOSIL 3PBr, 120 Å, 3 µm, 2 x 100 mm
Item number: CO-19347-71
Brand: Nacalai Tesque
$808.80
Product Image of HPLC Column COSMOSIL 3Cholester, 120 Å, 3 µm, 3 x 100 mm
HPLC Column COSMOSIL 3Cholester, 120 Å, 3 µm, 3 x 100 mm
Item number: CO-19196-51
Brand: Nacalai Tesque
$829.20
Product Image of HPLC Column COSMOSIL 3C18-AR-II, 120 Å, 3 µm, 4.6 x 250 mm
HPLC Column COSMOSIL 3C18-AR-II, 120 Å, 3 µm, 4.6 x 250 mm
Item number: CO-19391-81
Brand: Nacalai Tesque
$816.00
Product Image of COSMOSIL 5Diol-300-II Packed column, 5 µm, 7.5 mm ID x 600 mm
COSMOSIL 5Diol-300-II Packed column, 5 µm, 7.5 mm ID x 600 mm
Item number: CO-38054-11
Brand: Nacalai Tesque
$1,357.20
Product Image of COSMOSIL Buckyprep 120Å, 5 µm, 20.0 mm ID x 250 mm, price on request
COSMOSIL Buckyprep 120Å, 5 µm, 20.0 mm ID x 250 mm, price on request
Item number: CO-37982-81
Brand: Nacalai Tesque
$21,140.40
Product Image of HPLC column COSMOSIL PBr Packed column, 120Å, 5 µm, 20.0 mm ID x 50 mm
HPLC column COSMOSIL PBr Packed column, 120Å, 5 µm, 20.0 mm ID x 50 mm
Item number: CO-13257-31
Brand: Nacalai Tesque
$2,530.80
Product Image of HPLC column COSMOSIL PBr Packed column, 120Å, 5 µm, 10.0 mm ID x 150 mm
HPLC column COSMOSIL PBr Packed column, 120Å, 5 µm, 10.0 mm ID x 150 mm
Item number: CO-13255-51
Brand: Nacalai Tesque
$1,476.00
Product Image of COSMOSIL 2.5HILIC Packed column, 130Å, 2.5 µm, 3.0 mm ID x 75 mm
COSMOSIL 2.5HILIC Packed column, 130Å, 2.5 µm, 3.0 mm ID x 75 mm
Item number: CO-11772-31
Brand: Nacalai Tesque
$826.80
Product Image of COSMOSIL 2.5HILIC Packed column, 130Å, 2.5 µm, 2.0 mm ID x 75 mm
COSMOSIL 2.5HILIC Packed column, 130Å, 2.5 µm, 2.0 mm ID x 75 mm
Item number: CO-11768-01
Brand: Nacalai Tesque
$866.40
Product Image of COSMOSIL 3C18-EB Packed column, 120Å, 3 µm, 2.0 mm ID×75 mm
COSMOSIL 3C18-EB Packed column, 120Å, 3 µm, 2.0 mm ID×75 mm
Item number: CO-09795-11
Brand: Nacalai Tesque
$730.80
Product Image of COSMOSIL 5HIC Packed column, 300Å, 5 µm, 4.6 mm ID x 50 mm
COSMOSIL 5HIC Packed column, 300Å, 5 µm, 4.6 mm ID x 50 mm
Item number: CO-04263-21
Brand: Nacalai Tesque
$640.80
Product Image of HPLC Guard Cartridge COSMOSIL 3C18-PAQ, 120Å, 3µm, 2.0 x 10 mm, 2 pc/PAK
HPLC Guard Cartridge COSMOSIL 3C18-PAQ, 120Å, 3µm, 2.0 x 10 mm, 2 pc/PAK
Item number: CO-19874-74
Brand: Nacalai Tesque
$218.40
Product Image of HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 4.6 x 250 mm
HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 4.6 x 250 mm
Item number: CO-19873-71
Brand: Nacalai Tesque
$621.60
Product Image of HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 4.6 x 150 mm
HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 4.6 x 150 mm
Item number: CO-19872-81
Brand: Nacalai Tesque
$490.80
Product Image of HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 4.6 x 100 mm
HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 4.6 x 100 mm
Item number: CO-19871-91
Brand: Nacalai Tesque
$456.00
Product Image of HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 3.0 x 250 mm
HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 3.0 x 250 mm
Item number: CO-19789-91
Brand: Nacalai Tesque
$847.20
Product Image of HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 3.0 x 150 mm
HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 3.0 x 150 mm
Item number: CO-19788-01
Brand: Nacalai Tesque
$482.40
Product Image of HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 2.0 x 250 mm
HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 2.0 x 250 mm
Item number: CO-19781-71
Brand: Nacalai Tesque
$946.80
Product Image of HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 2.0 x 150 mm
HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 2.0 x 150 mm
Item number: CO-19780-81
Brand: Nacalai Tesque
$562.80
Product Image of HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 2.0 x 50 mm
HPLC Column COSMOSIL 3C18-PAQ packed, 120Å, 3 µm, 2.0 x 50 mm
Item number: CO-19773-81
Brand: Nacalai Tesque
$456.00

Items 1-50 of 419

nacalai tesque COSMOSIL HPLC-columns

The ‘Superb’ packing technique developed by Nacalai Tesque is used to produce the highly efficient HPLC columns. Totally porous silica particles are used, so that COSMOSIL columns have a higher chemical and mechanical stability as well as outstanding surface properties.

COSMOSIL ODS Columns

  • COSMOSIL 5C18-MS-II is a monomer-bound C18 phase with a new polar endcapping for better shielding of the surface resulting in extended pH stability and a significantly improved peak shape for basic compounds. It is a universal C18 phase and particularly effective for applications with low molecular organic compounds.
  • COSMOSIL 5C18-AR-II is a polymer-bound C18 phase that exhibits excellent stability and long life at low pH values. This phase is recommended for separation under acidic conditions and shows “shape selectivity" as opposed to monomer-bound C18 phases.
  • COSMOSIL 5C18-PAQ is a polar-modified C18 phase, specifically applied for the separation of polar compounds. It also shows excellent performance and reproducibility under 100% aqueous conditions.

COSMOSIL HPC-Columns – Special Selectivity

  • COSMOSIL Cholester is a reversed phase with a cholesteryl group. It exhibits a comparable hydrophobicity to traditional C18 phases, but also has enhanced stereoselectivity, especially in geometrical isomers and compounds with little structural differences.
  • COSMOSIL πNAP is a reversed phase with a naphthylethyl group that has stronger π-π interactions with unsaturated compounds than classical phenyl phases. In contrast to alkyl phases, the COSMOSIL πNAP offers a better separation of position isomers.
  • COSMOSIL PYE is a reversed phase with a 2- (1-pyrenyl) ethyl group. It shows a special retention characteristic based on several separation modes. For hydophobic and "charge transfer" interactions, this phase shows the strongest π-π interactions regarding the separation of structural isomers.
  • COSMOSIL HILIC is a special phase with a triazole group for Hydrophilic Interaction Chromatography (HILIC). Strongly polar compounds, which are not retained under reversed phase conditions, can be separated on this phase without any ion pair reagent. In addition, the phase shows a weak anion exchange mechanism with the positively charged stationary phase, so that even acidic compounds are well separated.
  • COSMOSIL Protein-R is a reversed phase specifically designed for the separation of proteins and peptides. The phase provides improved peak shapes through minimized tailing, higher recovery rates, and outstanding low pH stability compared to conventional Wide Pore 300Å C18 and C4 phases.
  • COSMOSIL Sugar-D is a novel phase, specifically designed for saccharide analysis. Compared to conventional aminopropyl phases, the COSMOSIL Sugar-D has an extended lifetime due to the novel "defense shield" protection, which simultaneously minimizes undesired adsorption of different saccharides.

Raw Material Silica Gel

COMSOSIL is based on ultra pure porous spherical silica gel (purity: 99.99% or higher). Low-purity silica gel contains metal impurity which may cause interference in the separation, especially for metal coordination compounds. 

Endcapping Treatment

The silanols (Si-OH groups) on the silica surface provided bonding site for stationary phases. However, part of the silanol groups remain un-capped as residual silanol groups even after the end-capping treatment, they cause peak tailing for basic compounds. COSMOSIL packing materials for reversed phase chromatography are of near-perfectly end-capped residual silanol groups.

Applications of the different HPLC Column Materials

  • organic components
Separation Type Packing Properties
Reversed Phase                3C18-EB Exzellent für Standardanalysen
Packungsmaterial: Silica, 3 µm 
C18-MS-II Mehrzweck-C18-Säule
Monofunktionelle Silylierung von hochreinem Silicagel für nahezu jede Trennung 
C18-AR-II Hohe Säureresistenz
Geeignet für saure Proben und Peptide 
C18-PAQ Kompatibel mit 100 % wässrigen mobilen Phasen
Geeignet für hydrophile Lösungen 
Cholester Erhöhte Trennleistung durch starre Cholesterylstrukturen
Vergleichbare Einsatzmöglichkeiten wie C18 
πNAP stärkere π-π-Wechselwirkung als bei Phenyl-Säulen
PYE bietet die stärksten π-π-Wechselwirkungen aller Säulen
NPE Trennung durch π-π- und Dipol-Dipol-Wechselwirkungen
PBB-R Trennung durch Nutzung von Dispersionskräften
C22-AR-II HPLC Säule mit Alkylketten
C8-MS HPLC Säule mit Alkylketten 
C4-MS  HPLC Säule mit Alkylketten 
TMS-MS HPLC Säule mit Alkylketten 
PE-MS  π-π-Wechselwirkung zwischen Produkt und stationärer Phase 
CN-MS  Hohe Reproduzierbarkeit unter Verwendung isokratischer Elutionen 
Normal Phase SL-II  Geeignet für präparative Trennungen 
Hydrophobic
Interactions 		 HILIC Hält hoch polare Komponenten zurück, die bei C18 eluiert werden würden

 

  • Mono- and Oligosaccharides
Separation Type
 Packing Properties
Hydrophobic
Interactions 		 Sugar-D Geeignet für Mono- und Disaccharide
NH2-MS HPLC Säule, welche primäre Amine binded

 

  • Proteins
Separation Type
 Packing Properties
Reversed Phase     Protein-R Hohe Trennleistung sowie Trennrate, Säurebeständig
C18-AR-300 Reversed Phase HPLC Säule mit unterschiedlichen Porengrößen
C8-AR-300  Reversed Phase HPLC Säule mit unterschiedlichen Porengrößen
C4-AR-300  Reversed Phase HPLC Säule mit unterschiedlichen Porengrößen 
Ph-AR-300  Reversed Phase HPLC Säule mit unterschiedlichen Porengrößen 
Gel Permeation Diol-120-II Silica basierte Gelfiltration
Auftrennung der Porengrößen: 5 000 - 100 000 
Diol-300-II Silica basierte Gelfiltration
Auftrennung der Porengrößen: 10 000 - 700 000 
Ion Exchange Type Q Anionenaustausch Säule für Aufreinigungen
Bevorzugte Proben: saure Proteine, DNA 
Type Q-N Anionenaustausch Säule für ultraschnelle, präzise Analysen
Bevorzugte Proben: saure Proteine, DNA 
Type S Kationenaustausch Säule für Aufreinigungen
Bevorzugte Proben: basische Proteine 
Type SN Kationenaustausch Säule für ultraschnelle, präzise Analysen
Bevorzugte Proben: basische Proteine 
Type M Amphotere Ionaustauschsäule für Aufreinigungen
Bevorzugte Proben: jede Art von Proteinen 
Type M-N Amphotere Ionenaustauschsäule für präzise Analysen
Bevorzugte Proben: jede Art von Proteinen 
Hydrophobic
Interactions		 HIC Geeignet zur Auftrennung von Proteinen, wobei Enzymaktivität und quartäre Struktur stark reduziert werden

 

  • Fullerenes
Separation Type
 Packing Properties
- Buckyprep Standardsäule für die Trennung von Fullerenen
Buckyprep-D Designed für die Trennung von Fullerenderivaten
Buckyprep-M Designed für die Trennung von Metallofullerenen
PBB Designed für die Trennung von C60, C70
PYE Trennung von Fullerenen und strukturellen Isomeren
NPE Trennung von Fullerenderivaten

 

  • Carbon Nanotubes
Separation Type
 Packing Properties
Gel Permeation CNT geeignet für die Trennung von Kohlenstoffnanotubes