HPLC Column Cogent Bidentate C18, 100 Å, 4 µm, 4.6 x 75 mm

Very unique C18 performance | Extremely hydrophobic | Use with 100% aqueous or non-polar solvents.

This phase is virtually indestructible due to the direct silicon-carbon bonds achieved when using our proprietary silica and bonding technologies. State of the art 4um or 2.2um high purity silica with a straight chain C18 hydrocarbon is bonded directly to the silica hydride surface with TWO (2) separate points of attachment for long column lifetimes even when using harsh HPLC conditions.

This column is the most stable, efficient and unique C18 column on the market and it can perform very well in reverse phase (RP), normal phase (ONP) or aqueous normal phase (ANP).

It requires less water for good retention of hydrophobic compounds, making gradient analysis so much easier. With no end capping, this phase can be used at very low pH without damage and is also much more stable when used with paired ion (PIC) reagents in RP.

Using this column in normal phase (NP) produces a very unusual mode of HPLC. Due to the lack of a water shell on all TYPE-C™ columns, it can separate water labile compounds without them degrading on column as occurs on regular Silica columns.