N-Methyl-N-trimethylsilyltrifluoroacetamide
Use Thermo Scientific™ MSTFA and MSTFA + 1% TMCS Silylation Reagent for GC analysis of early eluting compounds that would otherwise be missed in the chromatogram. MSTFA, the most volatile TMS amide available, and its byproduct N-methyltrifluoroacetamide typically elute with the solvent front, allowing the analysis of small molecule TMS derivatives. The addition of Thermo Scientific™ TMCS aids in the derivatization of amides, secondary amines and hindered hydroxyls that cannot be derivatized with MSTFA alone.
Trimethylsilyl donor strength comparable to BSA and BSTFA
Replaces labile hydrogens in a variety of polar compounds with a Si(CH3)3 group during the reaction
For use in the preparation of volatile and thermally stable derivatives for GC and MS
The volatile byproduct N-methyltrifluoroacetamide has an even lower retention time than MSTFA
Often, small molecule TMS derivatives can be analyzed when derivatized with MSTFA because the byproducts and the reagent itself usually elute with the solvent front
The addition of Thermo Scientific TMCS aids in the derivatization of amides, secondary amines and hindered hydroxyls that cannot be derivatized with MSTFA alone cannot be derivatized.
Brand | Thermo Fisher Scientific |
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Cas number | 24589-78-4 |
Concentration | 98-100% |
GHS classification | Warning |
Hazard Statements | H226, H315, H335, H319 |
Hazard Symbols | GHS02, GHS07 |
precautionary statements | P210, P233, P235, P261, P264, P271, P280, P302, P303, P304, P305, P338, P340, P351, P352, P353, P361, P370, P378, P403, P501 |
Volume / Package size | 25 ml |
GHS02
GHS07