HPLC Guard Column YMC-Pack C8, 1/16, 12nm, S-3 µm, 5 x 300 µm, 3pc/PAK

YMC-Pack C8: Features & Benefits

Available in three pore sizes, YMC-Pack C8 columns will separate many classes of compounds including pharmaceuticals, organic chemicals, and biologics.  For preparative applications, choose the smallest pore size which provides adequate retention and resolution.  This is due to the fact that sample loading is generally proportional to surface area, and small pore stationary phases provide greater surface area.

• Choice of 120Å, 200Å, or 300Å pore sizes
• Fully endcapped
• High coverage monomerically-bonded chemistry
• Available in analytical, semi preparative, and preparative column sizes

Monomerically Bonded, Fully Endcapped C8

C8 is the most commonly used column type following C18.  YMC-Pack C8 columns are prepared using exhaustive bonding of a monomeric octylsilane to totally porous and spherical silica gels.  The functionalized silica is then treated with an endcapping process which produces a moderate 10% carbon loading on the standard 120Å pore material.

Broad Application Range/p>

C8 columns are well-suited for the separation of many compounds which are too strongly retained on C18 phases or require greater retention than C4.  It is the most versatile reversed-phase column and should be considered a first choice when outfitting a new laboratory.